Edward M. Hawes

N+-glucuronidation, a common pathway in human metabolism of drugs with a tertiary amine group.

Edward M. Hawes · PubMed · 1998 · 103 citations

Life Sciences, Biochemistry, Pharmacology +14

N-oxygenation of clozapine by flavin-containing monooxygenase.

Meera Tugnait, Edward M. Hawes, G McKay et al. · PubMed · 1997 · 75 citations

Medicine, Biochemistry, Pharmacology +17

Microsomal formation of a pyrrolic alcohol glutathione conjugate of clivorine. Firm evidence for the formation of a pyrrolic metabolite of an otonecine-type pyrrolizidine alkaloid.

Ge Lin, Yan‐Yan Cui, Edward M. Hawes · PubMed · 1998 · 71 citations

Medicine, Biochemistry, Pharmacology +9

Characterization of Rat Liver Microsomal Metabolites of Clivorine, an Hepatotoxic Otonecine-Type Pyrrolizidine Alkaloid

Ge Lin, Yan‐Yan Cui, Edward M. Hawes · Drug Metabolism and Disposition · 2000 · 71 citations

Pharmacy, Pharmacology, Toxicology +13

Characterization of the human hepatic cytochromes P450 involved in the in vitro oxidation of clozapine

Meera Tugnait, Edward M. Hawes, Gordon McKay et al. · Chemico-Biological Interactions · 1999 · 58 citations

Medicine, Pharmacology, Drug Metabolism +12