Sean Kang

Valve-Related Hemodynamics Mediate Human Bicuspid Aortopathy

David G. Guzzardi, Alex J. Barker, Pim van Ooij et al. · Journal of the American College of Cardiology · 2015 · 422 citations

Cardiovascular Disease, Physiology, Valve Disease +4

Direct Effects of Empagliflozin on Extracellular Matrix Remodelling in Human Cardiac Myofibroblasts: Novel Translational Clues to Explain EMPA-REG OUTCOME Results

Sean Kang, Subodh Verma, Ali Fatehi Hassanabad et al. · Canadian Journal of Cardiology · 2019 · 164 citations

Mechanobiology, Cardiac Muscle, Cardiomyopathy +14

Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress

Mahmoud El‐Daly, Vivek Krishna Pulakazhi Venu, Mahmoud Saifeddine et al. · Vascular Pharmacology · 2018 · 111 citations

Hyperglycaemic Impairment, Metabolic Syndrome, Hypertension +13

Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair

H.E. Mewhort, Daniyil A. Svystonyuk, Jeannine D. Turnbull et al. · JACC Basic to Translational Science · 2017 · 63 citations · Full text

Tissue Engineering, Cardiac Muscle, Heart Failure +23

Induction of human aortic myofibroblast-mediated extracellular matrix dysregulation: A potential mechanism of fluoroquinolone-associated aortopathy

David G. Guzzardi, Guoqi Teng, Sean Kang et al. · Journal of Thoracic and Cardiovascular Surgery · 2018 · 57 citations · Full text

Inflammation, Fibrosis, Vascular Disease +9