Iris Castro

NFκB in Pancreatic Stellate Cells Reduces Infiltration of Tumors by Cytotoxic T Cells and Killing of Cancer Cells, via Up-regulation of CXCL12

Bharti Garg, Bhuwan Giri, Shrey Modi et al. · Gastroenterology · 2018 · 151 citations

Life Sciences, Cell Biology, Oncology +16

Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity

Alexey Berezhnoy, Iris Castro, Agata Levay et al. · Journal of Clinical Investigation · 2013 · 118 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Bruton’s Tyrosine Kinase Mediates NF-κB Activation and B Cell Survival by B Cell-Activating Factor Receptor of the TNF-R Family

Nicholas Shinners, Gianluca Carlesso, Iris Castro et al. · The Journal of Immunology · 2007 · 114 citations · Full text

Life Sciences, Immunology, Pathology +17

Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response

Felipe V. Pereira, Amanda Campelo Lima de Melo, Jun Siong Low et al. · Oncotarget · 2018 · 74 citations · Full text

Medicine, Immunology, Pharmacology +17

The Basis of Distinctive IL-2– and IL-15–Dependent Signaling: Weak CD122-Dependent Signaling Favors CD8+ T Central-Memory Cell Survival but Not T Effector-Memory Cell Development

Iris Castro, Aixin Yu, Michael J. Dee et al. · The Journal of Immunology · 2011 · 65 citations · Full text

Life Sciences, Cell Biology, Immunology +17