Patrick E. Georgoff

Safety and Tolerability of Intravenous Valproic Acid in Healthy Subjects: A Phase I Dose-Escalation Trial

Patrick E. Georgoff, Vahagn C. Nikolian, Tess Bonham et al. · Clinical Pharmacokinetics · 2017 · 51 citations · Full text

Drug Safety, Healthy Subjects, Medicine +8

Valproic acid decreases brain lesion size and improves neurologic recovery in swine subjected to traumatic brain injury, hemorrhagic shock, and polytrauma

Vahagn C. Nikolian, Patrick E. Georgoff, Manjunath P. Pai et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2017 · 50 citations

Improvement of Blood-Brain Barrier Integrity in Traumatic Brain Injury and Hemorrhagic Shock Following Treatment With Valproic Acid and Fresh Frozen Plasma

Vahagn C. Nikolian, Simone E. Dekker, Ted Bambakidis et al. · Critical Care Medicine · 2017 · 50 citations

Transcriptomic changes following valproic acid treatment promote neurogenesis and minimize secondary brain injury

Vahagn C. Nikolian, Isabel S. Dennahy, Gerald A. Higgins et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2017 · 35 citations · Full text

Resuscitation with Lyophilized Plasma Is Safe and Improves Neurological Recovery in a Long-Term Survival Model of Swine Subjected to Traumatic Brain Injury, Hemorrhagic Shock, and Polytrauma

Patrick E. Georgoff, Vahagn C. Nikolian, Ihab Halaweish et al. · Journal of Neurotrauma · 2017 · 34 citations

Trauma Resuscitation, Traumatic Brain Injury, Swine Subjected +13