Kenneth K. Chan

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

Muller Fabbri, Ramiro Garzon, Amelia Cimmino et al. · Proceedings of the National Academy of Sciences · 2007 · 1.7K citations · Full text

Life Sciences, Genetics, Oncology +14

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1

Ramiro Garzon, Shujun Liu, Muller Fabbri et al. · Blood · 2009 · 774 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms.

Victor Sandor, Susan Bakke, Robert W. Robey et al. · PubMed · 2002 · 510 citations

Medicine, Clinical Pharmacokinetics, Pharmacology +12

Clinical response and <i>miR-29b</i> predictive significance in older AML patients treated with a 10-day schedule of decitabine

William Blum, Ramiro Garzon, Rebecca B. Klisovic et al. · Proceedings of the National Academy of Sciences · 2010 · 453 citations · Full text

Medicine, Hematology, Pharmacology +13

Curcumin is a potent DNA hypomethylation agent

Zhongfa Liu, Zhiliang Xie, W.P. Jones et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 322 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +5