Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox

Jung-Hee Lee, Hoon Ryu, Robert J. Ferrante, +2

Proceedings of the National Academy of Sciences

Synthase ExpressionImmunologyMolecular BiologyCellular PhysiologyProtein Synthesis +23

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

Hoon Ryu, Jung-Hee Lee, Beatrix A. Olofsson, +7

Proceedings of the National Academy of Sciences

Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival

Jung-Hee Lee, Chun-Hyung Kim, David K. Simon, +10

Journal of Biological Chemistry

Mitochondrial DysfunctionSocial SciencesOxidative StressMolecular NeuroscienceMolecular Physiology +16

Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons

Hoon Ryu, Jung-Hee Lee, Soren Impey, +2

Proceedings of the National Academy of Sciences

Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease

Yeon Ha Ju, Mridula Bhalla, Seung Jae Hyeon, +12

Cell Metabolism

Neurodegenerative DiseasesAlzheimer's DiseaseMolecular NeuroscienceMedicinePhysiology +9

Prosurvival and Prodeath Effects of Hypoxia-inducible Factor-1α Stabilization in a Murine Hippocampal Cell Line

Leila R. Aminova, Juan C. Chávez, Jung-Hee Lee, +4

Journal of Biological Chemistry

Cell DeathRedox BiologyCellular PhysiologySocial SciencesOxidative Stress +17

Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease

Min Young Lee, Jung-Hee Lee, Seung Jae Hyeon, +9

Aging Cell

1H NMR-based metabonomic assessment of probiotic effects in a colitis mouse model

Young‐Shick Hong, Young‐Tae Ahn, Jong-Cherl Park, +6

Archives of Pharmacal Research

Nmr-based Metabonomic AssessmentProbioticSystems BiologyDysbiosisColitis Mouse Model +8

Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathy

Jeong‐Sun Seo, Seungbok Lee, Jong-Yeon Shin, +21

Experimental & Molecular Medicine

Reactive Astrocytes Express Bis, a Bcl-2-Binding Protein, after Transient Forebrain Ischemia

Mun‐Yong Lee, Seong-Yun Kim, Soon‐Lim Shin, +4

Experimental Neurology

Signal TransductionNeurophysiologyBrain-immune InteractionBcl-2-binding ProteinSocial Sciences +9