Comparative mammalian metabolism of adriamycin and daunorubicin.

Herbert Loveless, Emanuela Arena, Ronald L. Felsted, +1

PubMed

Adriamycin ReductionMolecular PharmacologyPharmacological StudyBiochemistrySkeletal Muscle +11

Anti‐amnesic properties of (±)‐PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats

Vuokko Antonini, Orazio Prezzavento, Marino Coradazzi, +4

Journal of Neurochemistry

Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells

Melania Olivieri, Emanuele Amata, Shila Vinciguerra, +11

Journal of Medicinal Chemistry

Ocular DiseaseImmunologyMolecular PharmacologyAngiogenesisNovel Prodrug +15

Synthesis and Resolution of<i>cis</i>-(±)-Methyl (1<i>R</i>,2<i>S</i>/1<i>S</i>,2<i>R</i>)-2-[(4-Hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate [(±)-PPCC)]: New σ Receptor Ligands with Neuroprotective Effect

Orazio Prezzavento, Agata Campisi, Carmela Parenti, +8

Journal of Medicinal Chemistry

Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands

Giuseppe Romeo, Orazio Prezzavento, Sebastiano Intagliata, +10

European Journal of Medicinal Chemistry

MedicineNew BenzoxazolePharmacologyPharmaceutical ChemistryDrug Discovery +1

Development of novel LP1-based analogues with enhanced delta opioid receptor profile

Lorella Pasquinucci, Rita Turnaturi, Orazio Prezzavento, +6

Bioorganic & Medicinal Chemistry

Molecular PharmacologyDrug TargetBiochemistryFunctional SelectivityMedicine +8

Synthesis and Biological Characterization of 3-Substituted-1<i>H</i>-indoles as Ligands of GluN2B-Containing <i>N</i>-Methyl-<scp>d</scp>-aspartate Receptors

Rosaria Gitto, Laura De Luca, Stefania Ferro, +10

Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryBiochemistryFunctional SelectivityMedicine +12

(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist

Lorella Pasquinucci, Rita Turnaturi, Girolamo Calò, +8

European Journal of Medicinal Chemistry

BiochemistryFunctional SelectivityMedicineMechanism Of ActionPharmacological Agent +5

(+)-Methyl (1<i>R</i>,2<i>S</i>)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties

Emanuele Amata, Antonio Rescifina, Orazio Prezzavento, +8

Journal of Medicinal Chemistry

Nanoencapsulation strategies for the delivery of novel bifunctional antioxidant/σ1 selective ligands

Claudia Carbone, Emanuela Arena, Veronica Pepe, +6

Colloids and Surfaces B Biointerfaces

NanotherapeuticsDrug Delivery SystemsNano-drug DeliveryChemistryDrug Delivery System +3