Concepedia

Jian Guan

JG

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Publications

14

Citations

1.3K

H-Index

14

Active since

2009

Affiliations

Brigham and Women's Hospital(Current)

Harvard University

Boston University

First Affiliated Hospital of Jinan University

University of Pavia

Jian Guan is an author at Brigham and Women's Hospital specializing in medicine, oxidative stress, and cell biology.

ORCID

Top concepts

Publications per year

2009–2024

14

Publications

14

Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38α MAPK pathway

Jianru Shi, Jian Guan, Bingbing Jiang et al. · Proceedings of the National Academy of Sciences · 2010 · 319 citations · Full text

Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis

Jennifer E. Ward, Ruiyi Ren, Gianluca Toraldo et al. · Blood · 2011 · 150 citations · Full text

Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish

Shikha Mishra, Jian Guan, Eva Plovie et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2013 · 145 citations · Full text

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Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity

Jian Guan, Shikha Mishra, Yiling Qiu et al. · EMBO Molecular Medicine · 2014 · 130 citations · Full text

A Novel Role for Tumor Necrosis Factor–Like Weak Inducer of Apoptosis (TWEAK) in the Development of Cardiac Dysfunction and Failure

Mohit Jain, Aniela Jakubowski, Lei Cui et al. · Circulation · 2009 · 114 citations · Full text

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