Paul H. J. Nederkoorn

Modelling and mutation studies on the histamine H1-receptor agonist binding site reveal different binding modes for H1-agonists: Asp116 (TM3) has a constitutive role in receptor stimulation

Antonius ter Laak, H. Timmerman, Rob Leurs et al. · Journal of Computer-Aided Molecular Design · 1995 · 54 citations

Histamine H1-receptor Agonist, Molecular Physiology, Signal Transduction +12

Development of a Pharmacophore Model for Histamine H₃ Receptor Antagonists, Using the Newly Developed Molecular Modeling Program SLATE

Iwan J. P. de Esch, James E. Mills, Timothy D. Perkins et al. · Journal of Medicinal Chemistry · 2001 · 40 citations · Full text

Density-Functional Study of (Solvated) Grignard Complexes

Andreas W. Ehlers, G.P.M. Van Klink, Maurice J. van Eis et al. · Journal of Molecular Modeling · 2000 · 33 citations

Inorganic Chemistry, Density-functional Study, Coordination Complex +2

A Qualitative Model for the Histamine H3 Receptor Explaining Agonistic and Antagonistic Activity Simultaneously

Iwan J. P. de Esch, Henk Timmerman, Wiro M. P. B. Menge et al. · Archiv der Pharmazie · 2000 · 28 citations

Drug Target, Qualitative Model, Pharmacotherapy +20

Development of a Three-Dimensional <i>CysLT</i><i>₁</i> (LTD₄) Antagonist Model with an Incorporated Amino Acid Residue from the Receptor

Mariël E. Zwaagstra, Saskia H. H. F. Schoenmakers, Paul H. J. Nederkoorn et al. · Journal of Medicinal Chemistry · 1998 · 28 citations · Full text