Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

Claus R. Bartram, Annelies de Klein, Anne Hagemeijer, +10

Nature

Chronic Myelocytic LeukaemiaChromatinHematological MalignancyPhiladelphia ChromosomeHematology +7

The Chronic Myelocytic Cell Line K562 Contains a Breakpoint in <i>bcr</i> and Produces a Chimeric <i>bcr</i>/<i>c</i>-<i>abl</i> Transcript

Gerard C. Grosveld, Theo C. Verwoerd, Ton van Agthoven, +5

Molecular and Cellular Biology

Mixed-phenotype Acute LeukemiaImmunologyMolecular BiologyCellular PhysiologyMyeloid Neoplasia +19

Functional Screen for Genes Responsible for Tamoxifen Resistance in Human Breast Cancer Cells

Daniëlle Meijer, Ton van Agthoven, Peter T. Bosma, +2

Molecular Cancer Research

Tumor BiologyBreast OncologyTamoxifen ResistanceTamoxifen-sensitive PhenotypeMedicine +12

Characterization of BCAR4, a novel oncogene causing endocrine resistance in human breast cancer cells

Marcia Godinho, Daniëlle Meijer, Buddy Setyono-Han, +2

Journal of Cellular Physiology

Molecular analysis of both translocation products of a Philadelphia-positive CML patient

Annelies de Klein, Ton van Agthoven, Cora Groffen, +3

Nucleic Acids Research

Expression of estrogen, progesterone and epidermal growth factor receptors in primary and metastatic breast cancer

Ton van Agthoven, Mieke Timmermans, Lambert C. J. Dorssers, +1

International Journal of Cancer

Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway

Lambert C. J. Dorssers, Ton van Agthoven, Arend Brinkman, +3

Breast Cancer Research

Selective recruitment of breast cancer anti-estrogen resistance genes and relevance for breast cancer progression and tamoxifen therapy response

Ton van Agthoven, Anieta M. Sieuwerts, Daniëlle Meijer, +6

Endocrine Related Cancer

Protein pathway activation mapping reveals molecular networks associated with antiestrogen resistance in breast cancer cell lines

Ton van Agthoven, Marcia Godinho, Julia Wulfkuhle, +2

International Journal of Cancer

Bcar GenesAntiestrogen ResistanceBreast OncologySignaling PathwayTamoxifen Resistance +11

BCAR3 regulates EGF-induced DNA synthesis in normal human breast MCF-12A cells

Myung-Ju Oh, Ton van Agthoven, Ji Eun Choi, +4

Biochemical and Biophysical Research Communications

Breast OncologyDevelopmental BiologyCell RegulationMedicineEgf-induced Dna Synthesis +6