A recently evolved hexose transporter variant confers resistance to multiple pathogens in wheat

John W. Moore, S. A. Herrera-Foessel, Caixia Lan, +15

Nature Genetics

Plant ImmunityDisease ResistanceGeneticsPathogenesisPlant Pathology +7

S-nitrosylation of NADPH oxidase regulates cell death in plant immunity

Byung‐Wook Yun, Angela Feechan, Minghui Yin, +9

Nature

BiologyPlant ImmunityBiochemistryNadph OxidaseNatural Sciences +9

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.

Heidi Sowter, Raju R. Raval, John W. Moore, +2

PubMed

Cell DeathRedox BiologyTranscriptional ResponseTumor BiologyTranscriptional Regulation +17

Spatial regulation of a zebrafish <i>patched</i> homologue reflects the roles of <i>sonic hedgehog</i> and protein kinase A in neural tube and somite patterning

Jean‐Paul Concordet, Katharine E. Lewis, John W. Moore, +4

Development

Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.

Christine Blancher, John W. Moore, Naomi Robertson, +1

PubMed

PathologyVon Hippel-lindauCancer BiologyTumor BiologyOxidative Stress +19

Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation.

Kevin Turner, John W. Moore, Adam Jones, +9

PubMed

Hypoxia-inducible FactorsRenal PathologyPathologyCancer BiologyHif-alpha Subunits +16

Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines.

Christine Blancher, John W. Moore, Kate Talks, +2

PubMed

Breast OncologyHypoxia-inducible FactorsPathologyMammary Gland DevelopmentTumor Biology +17

EndoPDI, a Novel Protein-disulfide Isomerase-like Protein That Is Preferentially Expressed in Endothelial Cells Acts as a Stress Survival Factor

D C Sullivan, John W. Moore, Joseph J. Boyle, +3

Journal of Biological Chemistry

Relation of vascular endothelial growth factor production to expression and regulation of hypoxia-inducible factor-1 alpha and hypoxia-inducible factor-2 alpha in human bladder tumors and cell lines.

Adam Jones, Chisato Fujiyama, C Blanche, +5

PubMed

Hypoxia-inducible Factor-2 AlphaHypoxia InducibilityPathologyTumor BiologyAngiogenesis +14

A mycobacterial iron chelator, desferri-exochelin, induces hypoxia-inducible factors 1 and 2, NIP3, and vascular endothelial growth factor in cancer cell lines.

Tsung Wen Chong, Lawrence D. Horwitz, John W. Moore, +2

PubMed

Iron MetabolismImmunologyPathologyMycobacterial Iron ChelatorRedox Biology +20