Ruth H. Hughes

A critical role for PfCRT K76T in Plasmodium falciparum verapamil‐reversible chloroquine resistance

Viswanathan Lakshmanan, Patrick G. Bray, Dominik Verdier-Pinard et al. · The EMBO Journal · 2005 · 207 citations · Full text

Medicine, Molecular Biology, Pharmacology +16

Isoquine and Related Amodiaquine Analogues:  A New Generation of Improved 4-Aminoquinoline Antimalarials

Paul M. O’Neill, Amira Mukhtar, Paul A. Stocks et al. · Journal of Medicinal Chemistry · 2003 · 142 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Evidence for a Common Non‐Heme Chelatable‐Iron‐Dependent Activation Mechanism for Semisynthetic and Synthetic Endoperoxide Antimalarial Drugs

Paul A. Stocks, Patrick G. Bray, Victoria Barton et al. · Angewandte Chemie International Edition · 2007 · 130 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

PfCRT and the <i>trans</i>‐vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX

Patrick G. Bray, Mathirut Mungthin, Ian M. Hastings et al. · Molecular Microbiology · 2006 · 94 citations · Full text

Life Sciences, Biology, Infectious Diseases +17

Evidence for a Common Non‐Heme Chelatable‐Iron‐Dependent Activation Mechanism for Semisynthetic and Synthetic Endoperoxide Antimalarial Drugs

Paul A. Stocks, Patrick G. Bray, Victoria Barton et al. · Angewandte Chemie · 2007 · 24 citations

Medicine, Medicinal Chemistry, Pharmacology +14