A genome-wide search for human type 1 diabetes susceptibility genes

June Davies, Yoshihiko Kawaguchi, Simon T. Bennett, +13

Nature

Genome-wide Association StudyGenetic DeterminantGeneticsDiabetesComplex Disease +4

CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3⁺ regulatory T cells in gastric cancer

Yoshiki Mizukami, Koji Kono, Yoshihiko Kawaguchi, +4

International Journal of Cancer

The Pro12→Ala Substitution in PPAR-γ Is Associated With Resistance to Development of Diabetes in the General Population

Hiroyuki Mori, Hiroshi Ikegami, Yoshihiko Kawaguchi, +21

Diabetes

GeneticsGenetic EpidemiologyInsulin SignalingGeneral PopulationObesity +21

Cloning of a novel member of the low-density lipoprotein receptor family

Patricia J. Hey, Rebecca C.J. Twells, Michael Phillips, +10

Gene

BiochemistryNatural SciencesMolecular BiologyVascular BiologyLipoprotein Metabolism +4

Asian-Specific HLA Haplotypes Reveal Heterogeneity of the Contribution of HLA-DR and -DQ Haplotypes to Susceptibility to Type 1 Diabetes.

Yumiko Kawabata, Hiroshi Ikegami, Yoshihiko Kawaguchi, +7

Diabetes

Hla-Dq HaplotypesGeneticsGenetic EpidemiologyHuman Polymorphism +16

Cetuximab induce antibody‐dependent cellular cytotoxicity against EGFR‐expressing esophageal squamous cell carcinoma

Yoshihiko Kawaguchi, Koji Kono, Kousaku Mimura, +3

International Journal of Cancer

Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor‐infiltrating lymphocytes, tumor‐draining lymph nodes and peripheral blood lymphocytes in patients with gastric cancer

Takanori Maruyama, Koji Kono, Yoshiki Mizukami, +5

Cancer Science

Lymphocyte DevelopmentT-regulatory CellImmune RegulationImmunologyPathology +22

Vaccination with multiple peptides derived from novel cancer‐testis antigens can induce specific T‐cell responses and clinical responses in advanced esophageal cancer

Koji Kono, Yoshiki Mizukami, Yataro Daigo, +7

Cancer Science

A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients

Francesco Cucca, Juliet V. Goy, Yoshihiko Kawaguchi, +6

Nature Genetics

HistocompatibilityType 1Autoimmune DiseaseGeneticsImmunology +7

Vascular endothelial growth factor inhibits the function of human mature dendritic cells mediated by VEGF receptor-2

Kousaku Mimura, Koji Kono, Akihiro Takahashi, +2

Cancer Immunology Immunotherapy

InflammationEndothelial Cell PathobiologyVegf Receptor-2AngiogenesisImmunology +8