James S. Hardwick

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

James S. Hardwick, Finny G. Kuruvilla, Jeffrey K. Tong et al. · Proceedings of the National Academy of Sciences · 1999 · 520 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12–rapamycinassociated protein

Randall T. Peterson, Bimal N. Desai, James S. Hardwick et al. · Proceedings of the National Academy of Sciences · 1999 · 489 citations

Life Sciences, Cell Biology, Molecular Biology +17

Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes

Guillermo Garcia‐Manero, Hui Yang, Carlos E. Bueso‐Ramos et al. · Blood · 2007 · 461 citations

Medicine, Hematology, Oncology +16

Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study

Evanthia Galanis, Kurt A. Jaeckle, Matthew J. Maurer et al. · Journal of Clinical Oncology · 2009 · 357 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad range of moderately emetogenic chemotherapies and tumor types: a randomized, double-blind study

Bernardo L. Rapoport, Karin Jordan, Judith A. Boice et al. · Supportive Care in Cancer · 2009 · 233 citations

Medicine, Oncology, Pharmacology +17