Josh Ballard

Biological Characterization of ARRY-142886 (AZD6244), a Potent, Highly Selective Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor

Tammie C. Yeh, Vivienne Marsh, Bryan A. Bernat et al. · Clinical Cancer Research · 2007 · 583 citations · Full text

Medicine, Oncology, Pharmacology +14

Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors

Allen A. Thomas, Yvan Le Huérou, Jason De Meese et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 58 citations · Full text

Life Sciences, Biochemistry, Pharmacology +6

Non-charged thiamine analogs as inhibitors of enzyme transketolase

Allen A. Thomas, Jason De Meese, Yvan Le Huérou et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 40 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +11

Preclinical development of ARRY-142886, a potent and selective MEK inhibitor

Eli Wallace, Tammie C. Yeh, Joe Lyssikatos et al. · Cancer Research · 2004 · 18 citations

Medicine, Cancer Biology, Pharmacology +15