Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived Substrates and Products*

M. Wada, Cynthia J. DeLong, Yu Hong, +14

Journal of Biological Chemistry

Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1

Gilad Rimon, Ranjinder S. Sidhu, Adam Lauver, +7

Proceedings of the National Academy of Sciences

Comparison of Cyclooxygenase-1 Crystal Structures: Cross-Talk between Monomers Comprising Cyclooxygenase-1 Homodimers,

Ranjinder S. Sidhu, Jullia Y. Lee, Chong Yuan, +1

Biochemistry

Aldo-keto ReductaseMolecular BiologyChemical BiologyMedicinal ChemistryBiosynthesis +15

Partnering between monomers of cyclooxygenase-2 homodimers

Chong Yuan, Caroline Jill Rieke, Gilad Rimon, +2

Proceedings of the National Academy of Sciences

Cyclooxygenase Allosterism, Fatty Acid-mediated Cross-talk between Monomers of Cyclooxygenase Homodimers

Chong Yuan, Ranjinder S. Sidhu, Dmitry Kuklev, +4

Journal of Biological Chemistry

Cyclooxygenase AllosterismBioorganic ChemistryMolecular BiologyPartner MonomerChemical Biology +15

Two Distinct Pathways for Cyclooxygenase-2 Protein Degradation

Uri Mbonye, Chong Yuan, Clair Harris, +4

Journal of Biological Chemistry

Different Fatty Acids Compete with Arachidonic Acid for Binding to the Allosteric or Catalytic Subunits of Cyclooxygenases to Regulate Prostanoid Synthesis

Liang Dong, He-Chang Zou, Chong Yuan, +3

Journal of Biological Chemistry

BiosynthesisEngineeringLipid SynthesisBiochemistryOxysterol +5

Direct enzymatic assay for %HbA1c in human whole blood samples

Stefanie Hood, Yuping Wang, Robert E Bezverkov, +3

Clinical Biochemistry

Laboratory HematologyBiochemistryMedicineBioanalysisPharmacology +5

Asymmetric Acetylation of the Cyclooxygenase-2 Homodimer by Aspirin and Its Effects on the Oxygenation of Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids

Narayan Prasad Sharma, Liang Dong, Chong Yuan, +2

Molecular Pharmacology

Human cyclooxygenase-1 activity and its responses to COX inhibitors are allosterically regulated by nonsubstrate fatty acids

He-Chang Zou, Chong Yuan, Liang Dong, +4

Journal of Lipid Research