Takashi Machida

Identification of a Defect in the UGT1A1 Gene Promoter and Its Association with Hyperbilirubinemia

Junko Sugatani, Kasumi Yamakawa, Kouichi Yoshinari et al. · Biochemical and Biophysical Research Communications · 2002 · 208 citations

Genetic Disorder, Medicine, Genetics +10

Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro

Fuyuko Takata, Shinya Dohgu, Junichi Matsumoto et al. · Journal of Neuroinflammation · 2011 · 194 citations · Full text

TNF-α-sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways

Junichi Matsumoto, Shinya Dohgu, Fuyuko Takata et al. · Brain Research · 2018 · 102 citations

Inflammation, Jak-stat3 Pathways, Cytokine +11

Tumor necrosis factor-α-stimulated brain pericytes possess a unique cytokine and chemokine release profile and enhance microglial activation

Junichi Matsumoto, Fuyuko Takata, Takashi Machida et al. · Neuroscience Letters · 2014 · 96 citations

Inflammation, Cytokine, Microglial Activation +12

Metformin induces up-regulation of blood–brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells

Fuyuko Takata, Shinya Dohgu, Junichi Matsumoto et al. · Biochemical and Biophysical Research Communications · 2013 · 78 citations

Molecular Physiology, Blood–brain Barrier Functions, Neurophysiology +12