David G. Witte

Two Novel and Selective Nonimidazole Histamine H3 Receptor Antagonists A-304121 and A-317920: I. In Vitro Pharmacological Effects

Timothy A. Esbenshade, Kathleen M. Krueger, Thomas R. Miller et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 102 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Pharmacological Properties of ABT-239 [4-(2-{2-[(2 R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and Selective Histamine H3 Receptor Antagonist with Drug-Like Properties

Timothy A. Esbenshade, Gerard B. Fox, Kathleen M. Krueger et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 100 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist

Arthur A. Hancock, Youssef L. Bennani, Eugene N. Bush et al. · European Journal of Pharmacology · 2004 · 98 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6

H4 receptor antagonism exhibits anti-nociceptive effects in inflammatory and neuropathic pain models in rats

Gin C. Hsieh, Prasant Chandran, Anita K. Salyers et al. · Pharmacology Biochemistry and Behavior · 2009 · 82 citations

Medicine, Neuroscience, Pharmacology +16

Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H₄Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models

Marlon Cowart, Robert J. Altenbach, Huaqing Liu et al. · Journal of Medicinal Chemistry · 2008 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16