Krishnamoorthy Chandrasekhar

Structure of the Pyruvate Dehydrogenase Multienzyme Complex E1 Component from<i>Escherichia coli</i>at 1.85 Å Resolution^,

Palaniappa Arjunan, Natalia S. Nemeria, Andrew P. J. Brunskill et al. · Biochemistry · 2002 · 138 citations

A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct

Palaniappa Arjunan, Martin Sax, Andrew P. J. Brunskill et al. · Journal of Biological Chemistry · 2006 · 99 citations · Full text

Crystal Structure, Aldo-keto Reductase, Cellular Enzymology +13

Insight to the Interaction of the Dihydrolipoamide Acetyltransferase (E2) Core with the Peripheral Components in the Escherichia coli Pyruvate Dehydrogenase Complex via Multifaceted Structural Approaches

Krishnamoorthy Chandrasekhar, Junjie Wang, Palaniappa Arjunan et al. · Journal of Biological Chemistry · 2013 · 53 citations · Full text

Structure and Function of the Catalytic Domain of the Dihydrolipoyl Acetyltransferase Component in Escherichia coli Pyruvate Dehydrogenase Complex

Junjie Wang, Natalia S. Nemeria, Krishnamoorthy Chandrasekhar et al. · Journal of Biological Chemistry · 2014 · 47 citations · Full text

Catalytic Domain, Biosynthesis, Cellular Enzymology +7

Structural Determinants of Enzyme Binding Affinity:  The E1 Component of Pyruvate Dehydrogenase from <i>Escherichia coli</i> in Complex with the Inhibitor Thiamin Thiazolone Diphosphate^,

Palaniappa Arjunan, Krishnamoorthy Chandrasekhar, Martin Sax et al. · Biochemistry · 2004 · 44 citations