Thomas G. Metzger

Potent and Selective Indolomorphinan Antagonists of the Kappa-Opioid Receptor

William C. Stevens, Robert M. Jones, Govindan Subramanian et al. · Journal of Medicinal Chemistry · 2000 · 98 citations · Full text

Investigation of the Selectivity of Oxymorphone- and Naltrexone-Derived Ligands via Site-Directed Mutagenesis of Opioid Receptors:  Exploring the ‘Address' Recognition Locus

Thomas G. Metzger, Marta Paterlini, David M. Ferguson et al. · Journal of Medicinal Chemistry · 2001 · 82 citations · Full text

Application of the message-address concept to the docking of naltrexone and selective naltrexone-derived opioid antagonists into opioid receptor models

Thomas G. Metzger, Marta Paterlini, Philip S. Portoghese et al. · Neurochemical Research · 1996 · 75 citations

Opioid Epidemic, Opioid Receptor Models, Message-address Concept +10

Transformation of a κ-Opioid Receptor Antagonist to a κ-Agonist by Transfer of a Guanidinium Group from the 5‘- to 6‘-Position of Naltrindole

Shiv K. Sharma, Robert M. Jones, Thomas G. Metzger et al. · Journal of Medicinal Chemistry · 2001 · 64 citations · Full text

Isosteric Replacement of Acidic with Neutral Residues in Extracellular Loop-2 of the κ-Opioid Receptor Does Not Affect Dynorphin A(1−13) Affinity and Function

David M. Ferguson, Stacy Kramer, Thomas G. Metzger et al. · Journal of Medicinal Chemistry · 2000 · 25 citations · Full text

Altmetric Attention Score, Peptide Science, Pharmacotherapy +21