Shi‐Fang Yan

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.

A.M. Schmidt, Osamu Hori, J X Chen et al. · Journal of Clinical Investigation · 1995 · 893 citations · Full text

Vascular Disease, Immunology, Accelerated Vasculopathy +19

Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke.

E. Sander Connolly, Christopher J. Winfree, Timothy A. Springer et al. · Journal of Clinical Investigation · 1996 · 527 citations · Full text

Pmns Contribute, Immunology, Cerebrovascular Disease +21

Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis

Tomoyuki Fujita, Köichi Toda, Ann Karimova et al. · Nature Medicine · 2001 · 398 citations

Acute Lung Injury, Inhaled Carbon Monoxide, Paradoxical Rescue +6

The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis.

Toshio Miyata, Osamu Hori, Jian Zhang et al. · Journal of Clinical Investigation · 1996 · 286 citations · Full text

Immunology, Glycobiology, Immune Regulation +20

CD18-Mediated Neutrophil Recruitment Contributes to the Pathogenesis of Reperfused but Not Nonreperfused Stroke

Charles J. Prestigiacomo, Samuel Kim, E. Sander Connolly et al. · Stroke · 1999 · 180 citations