Keith J. M. Moore

Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in determining the transforming ability of ras.

John F. Eccleston, Keith J. M. Moore, Leslie K. Morgan et al. · Journal of Biological Chemistry · 1993 · 106 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Fluorescence correlation spectroscopy: lead discovery by miniaturized HTS

Manfred Auer, Keith J. M. Moore, Franz‐Josef Meyer‐Almes et al. · Drug Discovery Today · 1998 · 103 citations

Natural Sciences, Biochemistry, Chemistry +12

Single-turnover kinetics of helicase-catalyzed DNA unwinding monitored continuously by fluorescence energy transfer

Keith P. Bjornson, Mohan Amaratunga, Keith J. M. Moore et al. · Biochemistry · 1994 · 93 citations

Life Sciences, Biochemistry, Molecular Biology +16

Interaction of GTPase activating proteins (GAPs) with p21ras measured by a novel fluorescence anisotropy method. Essential role of Arg-903 of GAP in activation of GTP hydrolysis on p21ras

Geoffrey G. Brownbridge, Peter N. Lowe, Keith J. M. Moore et al. · Journal of Biological Chemistry · 1993 · 80 citations · Full text

Life Sciences, Cell Biology, Cell Signaling +3

Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: Studies with a fluorescent GTP analog

Keith J. M. Moore, Martin R. Webb, John F. Eccleston · Biochemistry · 1993 · 68 citations

Life Sciences, Biochemistry, Molecular Biology +16