Geoffrey W. Krystal

Activating c-kit Gene Mutations in Human Germ Cell Tumors

Q Tian, Henry F. Frierson, Geoffrey W. Krystal et al. · American Journal Of Pathology · 1999 · 409 citations · Full text

Tumor Biology, Somatic Variant, Germ Cell +5

Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor.

Geoffrey W. Krystal, Susan J. Hines, Craig P. Organ · PubMed · 1996 · 270 citations

Immunology, Cell Proliferation, Autocrine Growth +18

The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth.

Geoffrey W. Krystal, Sittisak Honsawek, Julie Litz et al. · PubMed · 2000 · 267 citations

Oncology, Chemoprevention Strategy, Tumor Microenvironment +15

Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.

Chunrong Yu, Geoffrey W. Krystal, Lyuba Varticovksi et al. · PubMed · 2002 · 192 citations

Chemoprevention Strategy, Bcr-abl Kinase, Apoptosis +16

The Insulin-Like Growth Factor-I Receptor Kinase Inhibitor, NVP-ADW742, Sensitizes Small Cell Lung Cancer Cell Lines to the Effects of Chemotherapy

G. Sakuntala Warshamana-Greene, Julie Litz, Elisabeth Buchdunger et al. · Clinical Cancer Research · 2005 · 189 citations