Alvin Lo

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

Britta Weigelt, Alvin Lo, Catherine C. Park et al. · Breast Cancer Research and Treatment · 2009 · 320 citations

Her2-targeting Agents, Breast Oncology, Cell Regulation +12

Patterned Collagen Fibers Orient Branching Mammary Epithelium through Distinct Signaling Modules

Douglas Brownfield, Gautham Venugopalan, Alvin Lo et al. · Current Biology · 2013 · 160 citations · Full text

Distinct Signaling Modules, Cell Lineage, Developmental Biology +9

Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1

Hidetoshi Mori, Alvin Lo, Jamie L. Inman et al. · Development · 2012 · 104 citations · Full text

Cancer Biology, Cellular Physiology, Mammary Gland Development +19

Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo

Alain Béliveau, Joni D. Mott, Alvin Lo et al. · Genes & Development · 2010 · 102 citations · Full text

Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells

Sylvia Fong, Mark Shoemaker, Jaclyn Cadaoas et al. · Cancer Biology & Therapy · 2008 · 44 citations · Full text

Scutellaria Barbata, Oncology, Oncogenic Agent +14