Chunlan Pu

Assessing the performance of docking scoring function, FEP, MM-GBSA, and QM/MM-GBSA approaches on a series of PLK1 inhibitors

Chunlan Pu, Guoyi Yan, Jianyou Shi et al. · MedChemComm · 2017 · 54 citations · Full text

Discovery of a PROTAC targeting ALK with in vivo activity

Guoyi Yan, Xin-Xin Zhong, Yue Lin et al. · European Journal of Medicinal Chemistry · 2021 · 47 citations · Full text

Vivo Activity, Drug Target, Signal Transduction +7

Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancer

Chunlan Pu, Yu Tong, Yuanyuan Liu et al. · European Journal of Medicinal Chemistry · 2022 · 40 citations · Full text

Breast Oncology, Medicine, Breast Cancer +8

Synthesis and biological evaluation of novel 2,3-dihydrochromeno[3,4-d]imidazol-4(1H)-one derivatives as potent anticancer cell proliferation and migration agents

Xuan Han, Luo Jiang, Feng Wu et al. · European Journal of Medicinal Chemistry · 2016 · 35 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +10

Development of PROTAC degrader probe of CDK4/6 based on DCAF16

Chunlan Pu, Yuanyuan Liu, Rui Deng et al. · Bioorganic Chemistry · 2023 · 34 citations

Biochemistry, Natural Sciences, Molecular Biology +3