Takuma Iguchi

A Novel HER3-Targeting Antibody–Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization

Yuuri Hashimoto, Kumiko Koyama, Yasuki Kamai et al. · Clinical Cancer Research · 2019 · 164 citations

En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH

Masaki Kimura, Takuma Iguchi, Kentaro Iwasawa et al. · Cell · 2022 · 99 citations · Full text

Metabolic Syndrome, Systems Biology, Genetics +7

Hedgehog signaling through GLI1 and GLI2 is required for epithelial–mesenchymal transition in human trophoblasts

Chao Tang, Liu Mei, Liyu Pan et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2015 · 50 citations

Developmental Biology, Tissue Development, Human Trophoblasts +8

Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology

Yusuke Ogitani, Yuki Abe, Takuma Iguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 50 citations

Wide Application, Medicinal Chemistry, Drug Targeting +12

Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody–Drug Conjugate

Kenji Iida, Amr H. Abdelhamid Ahmed, Akiko Kawano Nagatsuma et al. · Cancer Discovery · 2021 · 45 citations