Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis

Zhongyang Lv, Jie Han, Jiawei Li, +21

EBioMedicine

Targeted pathological collagen delivery of sustained-release rapamycin to prevent heterotopic ossification

Yangwu Chen, Weiliang Shen, Chenqi Tang, +8

Science Advances

3D printing of chemical-empowered tendon stem/progenitor cells for functional tissue repair

Yanjie Zhang, Tingyun Lei, Chenqi Tang, +17

Biomaterials

Tissue EngineeringRegenerative MedicineEngineeringBioprintingBiomaterials Design +11

Single-cell RNA-seq reveals novel mitochondria-related musculoskeletal cell populations during adult axolotl limb regeneration process

Tian Qin, Chunmei Fan, Tingzhang Wang, +14

Cell Death and Differentiation

Regenerative MedicineRegenerationCell LineageDevelopmental BiologySingle Cell Sequencing +7

Cell-subpopulation alteration and FGF7 activation regulate the function of tendon stem/progenitor cells in 3D microenvironment revealed by single-cell analysis

Hong Zhang, Yangwu Chen, Chunmei Fan, +6

Biomaterials

Regenerative MedicineMechanobiologyTendon Stem/progenitor CellsDevelopmental BiologyHealth Sciences +13

Discovery of Muscle-Tendon Progenitor Subpopulation in Human Myotendinous Junction at Single-Cell Resolution

Ruojin Yan, Hong Zhang, Yuanzhu Ma, +11

Research

Inhibition of ROS activity by controlled release of proanthocyanidins from mesoporous silica nanocomposites effectively ameliorates heterotopic ossification in tendon

Richun Liu, Bo Zhou, Hong Zhang, +10

Chemical Engineering Journal

Tissue EngineeringEngineeringRos ActivityOsteoarthritisTendon Injury +4

Evidence of Antisense Tumor Targeting in Mice

K. Nakamura, Chunmei Fan, G. Liu, +6

Bioconjugate Chemistry

Single-cell RNA-seq reveals functionally distinct biomaterial degradation-related macrophage populations

Jiayun Huang, Chunmei Fan, Yangwu Chen, +14

Biomaterials

Single Cell SequencingMedicineSingle-cell Rna-seq RevealsSingle-cell GenomicsSingle-cell Analysis +1

A Cd9+Cd271+ stem/progenitor population and the SHP2 pathway contribute to neonatal-to-adult switching that regulates tendon maturation

Chunmei Fan, Yanyan Zhao, Yangwu Chen, +12

Cell Reports