Takayuki Yoshioka

Experimental metastasis is suppressed in MMP-9-deficient mice

Takeshi Itoh, Masatoshi Tanioka, Hidetoshi Matsuda et al. · Clinical & Experimental Metastasis · 1999 · 306 citations

Anticancer efficacy in vivo and in vitro, synergy with 5-fluorouracil, and safety of recombinant methioninase.

Takayuki Yoshioka, Tsutomu Wada, Naoshige Uchida et al. · PubMed · 1998 · 147 citations

Chemoprevention Strategy, Immunology, Pharmacotherapy +18

In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.

Xinghua Sun, Zhijian Yang, Shukuan Li et al. · PubMed · 2003 · 87 citations

Engineering, Tumor Biology, Pyridoxal 5'-Phosphate Supplementation +16

Pharmacokinetics, Methionine Depletion, and Antigenicity of Recombinant Methioninase in Primates

Zhijian Yang, Junhua Wang, Takayuki Yoshioka et al. · Clinical Cancer Research · 2004 · 75 citations · Full text

Structure of the Antitumour Enzyme L-Methionine  -Lyase from Pseudomonas putida at 1.8 A Resolution

Daizou Kudou, S. Misaki, Miho Yamashita et al. · The Journal of Biochemistry · 2007 · 74 citations

Protein Chemistry, Biochemistry, Biomolecular Structure Prediction +13