The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration

Yang Liu, Linqing Miao, Feisi Liang, +6

Nature Communications

Mtorc1 Effectors S6k1NeuroregenerationDevelopmental BiologyMolecular NeuroscienceNeural Stem Cell +8

mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system

Linqing Miao, Yang Liu, Haoliang Huang, +3

eLife

Akt3-induced Axon RegenerationSynaptic SignalingCellular PhysiologySocial SciencesNeuroregeneration +16

Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules

Liu Yang, Shaohua Li, Linqing Miao, +11

Journal of Neuroscience

Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse

Jie Zhang, Liang Li, Haoliang Huang, +12

eLife

Neurodegenerative DiseasesOcular DiseaseMolecular PhysiologyDevelopmental BiologyOphthalmology +13

Mouse γ-Synuclein Promoter-Mediated Gene Expression and Editing in Mammalian Retinal Ganglion Cells

Qizhao Wang, Pei Zhuang, Haoliang Huang, +13

Journal of Neuroscience

Longitudinal Morphological and Functional Assessment of RGC Neurodegeneration After Optic Nerve Crush in Mouse

Liang Li, Haoliang Huang, Fang Fang, +3

Frontiers in Cellular Neuroscience

NMNAT2 is downregulated in glaucomatous RGCs, and RGC-specific gene therapy rescues neurodegeneration and visual function

Fang Fang, Pei Zhuang, Xue Feng, +10

Molecular Therapy

Neuroprotection by eIF2α-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss

Haoliang Huang, Linqing Miao, Feisi Liang, +8

Cell Death and Disease

Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes

Liang Li, Fang Fang, Xue Feng, +8

Neuron

Ganglion CellPhotoreceptor CellDevelopmental BiologyMolecular NeuroscienceRetina +9

AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration

Haoliang Huang, Linqing Miao, Yang Liu, +5

Cell Death and Disease