Sam Gandy

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David Borchelt, Gopal Thinakaran, Christopher B. Eckman et al. · Neuron · 1996 · 1.5K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

Gopal Thinakaran, David Borchelt, Michael K. Lee et al. · Neuron · 1996 · 1K citations · Full text

Life Sciences, Biochemistry, Enzymology +3

Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

Ben Readhead, Jean‐Vianney Haure‐Mirande, Cory C. Funk et al. · Neuron · 2018 · 729 citations · Full text

Life Sciences, Neurology, Neuroscience +11

Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

Weiping Qin, Tianle Yang, Lap Ho et al. · Journal of Biological Chemistry · 2006 · 619 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease

Minghui Wang, Noam D. Beckmann, Panos Roussos et al. · Scientific Data · 2018 · 605 citations · Full text

Life Sciences, Neurology, Neuroscience +17