Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice

Yasuhiko Yamamoto, Ichiro Kato, Toshio Doi, +9

Journal of Clinical Investigation

Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-1.

Toshio Doi, Liliane J. Striker, Carol J. Quaife, +4

PubMed

RAGE Control of Diabetic Nephropathy in a Mouse Model

K.M. Myint, Yasuhiko Yamamoto, Toshio Doi, +12

Diabetes

GlomerulonephritisRenal FunctionMedicinePhysiologyDiabetes +9

Transforming growth factor-beta. Murine glomerular receptors and responses of isolated glomerular cells.

Karen Mackay, Liliane J. Striker, Joseph Stauffer, +2

Journal of Clinical Investigation

Murine Glomerular ReceptorsMesangial Cell ProliferationImmunologyRenal InflammationGrowth Factor-beta +21

Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy

Hiroshi Kanamori, Takeshi Matsubara, Akira Mima, +10

Biochemical and Biophysical Research Communications

InflammationMetabolic SyndromeMcp-1/ccr2 PathwayRenal FunctionMedicine +9

Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy

Kojiro Nagai, Takeshi Matsubara, Akira Mima, +10

Kidney International

Akt/mtor-mediated Mesangial HypertrophyMedicineDiabetesPhysiologyDiabetic Kidney Disease +3

525 Safety and efficacy of pembrolizumab (MK-3475) in patients (pts) with advanced biliary tract cancer: Interim results of KEYNOTE-028

Yung‐Jue Bang, Toshio Doi, Filippo de Braud, +9

European Journal of Cancer

Gastrointestinal OncologyMedicineBiliary CancerPathologyInterim Results +4

A Vitamin D Analog Ameliorates Glomerular Injury on Rat Glomerulonephritis

Kojiro Makibayashi, Mitsuyoshi Tatematsu, Michinori Hirata, +8

American Journal Of Pathology

Glomerular DiseaseInflammationGlomerulonephritisRenal FunctionMedicine +9

Gas6 Regulates Mesangial Cell Proliferation through Axl in Experimental Glomerulonephritis

Motoko Yanagita, Hidenori Arai, Kenji Ishii, +7

American Journal Of Pathology

Glomerular DiseaseGlomerulonephritisInflammationUrologySignal Transduction +13

Growth Arrest-specific Gene 6 Is Involved in Glomerular Hypertrophy in the Early Stage of Diabetic Nephropathy

Kojiro Nagai, Hidenori Arai, Motoko Yanagita, +7

Journal of Biological Chemistry