Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models

Yoko Irukayama‐Tomobe, Yasuhiro Ogawa, Hiromu Tominaga, +12

Proceedings of the National Academy of Sciences

Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists

Takashi Nagahara, Tsuyoshi Saitoh, Noriki Kutsumura, +8

Journal of Medicinal Chemistry

Sleep DisordersPharmacotherapyChemical BiologyMolecular PharmacologyOrexin Receptor Agonists +19

Analgesic Effect of a Herbal Medicine for Treatment of Primary Dysmenorrhea - A Double-blind Study

Naoki Kotani, Tsutomu Oyama, Ichiro Sakai, +4

The American Journal of Chinese Medicine

Pain MedicineGynecologyMenstrual CycleReproductive EndocrinologyPain Management +15

Peripherally administered orexin improves survival of mice with endotoxin shock

Yasuhiro Ogawa, Yoko Irukayama‐Tomobe, Nobuyuki Murakoshi, +12

eLife

ImmunotoxicologyImmunologyCell DeathOxidative StressNeuroinflammation +17

Novel protocol combining physical and nutrition therapies, Intensive Goal-directed REhabilitation with Electrical muscle stimulation and Nutrition (IGREEN) care bundle

Hidehiko Nakano, Hiromu Naraba, Hideki Hashimoto, +8

Critical Care

Design and Synthesis of Potent and Highly Selective Orexin 1 Receptor Antagonists with a Morphinan Skeleton and Their Pharmacologies

Hiroshi Nagase, Naoshi Yamamoto, Masahiro Yata, +13

Journal of Medicinal Chemistry

Effects of gadolinium injected into the middle ear on the stria vascularis

Akinobu Kakigi, Masahiko Nishimura, Taizo Takeda, +3

Acta Oto-Laryngologica

Bragg reflection band width and optical rotatory dispersion of cubic blue-phase liquid crystals

Hiroyuki Yoshida, Konkanok Anucha, Yasuhiro Ogawa, +4

Physical review. E

Electric Field Tuning of Plasmonic Absorption of Metallic Grating with Twisted Nematic Liquid Crystal

Masayoshi Ojima, N. Numata, Yasuhiro Ogawa, +4

Applied Physics Express

EngineeringNegative-index MetamaterialPlasmonic AbsorptionMetamaterialsElectromagnetic Metamaterials +16

Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4,5-epoxy ring for binding with orexin 1 receptor

Naoshi Yamamoto, Sayaka Ohrui, Takahiro Okada, +12

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyBiochemistryFunctional SelectivityMedicineEssential Structure +7