Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P

Ruijuan Xu, Junfei Jin, Wei Hu, +6

The FASEB Journal

ApoptosisCell DeathCellular PhysiologyOxidative StressSerum Deprivation +17

Alkaline Ceramidase 3 (ACER3) Hydrolyzes Unsaturated Long-chain Ceramides, and Its Down-regulation Inhibits Both Cell Proliferation and Apoptosis

Wei Hu, Ruijuan Xu, Wei Sun, +4

Journal of Biological Chemistry

High susceptibility of a human breast epithelial cell type with stem cell characteristics to telomerase activation and immortalization.

Wei Sun, Kyung‐Sun Kang, I Morita, +2

PubMed

Human CellStem Cell CharacteristicsDevelopmental BiologyType Ii CellsHigh Susceptibility +13

Substrate Specificity, Membrane Topology, and Activity Regulation of Human Alkaline Ceramidase 2 (ACER2)

Wei Sun, Junfei Jin, Ruijuan Xu, +5

Journal of Biological Chemistry

Proteinlipid InteractionBiochemistryActivity RegulationNatural SciencesMembrane Topology +3

Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain

Kai Wang, Ruijuan Xu, Jennifer Schrandt, +17

PLoS Genetics

Neurological DisorderCell DeathNeurochemical BiomarkersOxidative StressNeuroinflammation +16

Houttuynia cordata polysaccharide alleviated intestinal injury and modulated intestinal microbiota in H1N1 virus infected mice

Mei‐Yu Chen, Hong Li, Xiaoxiao Lu, +5

Chinese Journal of Natural Medicines

Mucosal ImmunologyIntestinal InjuryHouttuynia CordataPathogenesisImmunology +8

Synthesis of partially fluorinated analogs of (Z)-5-decenyl acetate: probes for hydrophobic interaction in pheromone reception

Wei Sun, Chi Shing Ng, Glenn D. Prestwich

The Journal of Organic Chemistry

EngineeringChemical AnalysisAltmetric Attention ScoreOrganic ChemistryChemistry +16

Effect of electromagnetic field exposure on chemically induced differentiation of friend erythroleukemia cells.

Guojun Chen, Brad L. Upham, Wei Sun, +5

Environmental Health Perspectives

Radiation EffectRadiation ExposureElectromagnetic Field ExposureRadiation BiologyTumor Biology +14

Alkaline Ceramidase 2 (ACER2) and Its Product Dihydrosphingosine Mediate the Cytotoxicity of N-(4-Hydroxyphenyl)retinamide in Tumor Cells

Zhehao Mao, Wei Sun, Ruijuan Xu, +5

Journal of Biological Chemistry

Ocular DiseaseChemoprevention StrategyCell DeathTumor CellsCell Proliferation +15

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes

Ruijuan Xu, Wei Sun, Junfei Jin, +2

The FASEB Journal