Mohammad Mahdi Moein

Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs

Nicola Colclough, Kan Chen, Peter Johnström et al. · Clinical Cancer Research · 2020 · 233 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

A PET study in healthy subjects of brain exposure of ¹¹ C-labelled osimertinib – A drug intended for treatment of brain metastases in non-small cell lung cancer

Andrea Varrone, Katarina Varnäs, Aurelija Jučaitė et al. · Journal of Cerebral Blood Flow & Metabolism · 2019 · 54 citations · Full text

Medicine, Nuclear Medicine, Pharmacology +17

Synthesis and preclinical evaluation of [18F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B

Kenneth Dahl, Vadim Bernard‐Gauthier, Sangram Nag et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 24 citations

Medicine, Nuclear Medicine, Pharmacology +13

The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans

Katarina Varnäs, Zsolt Cselényi, Ryosuke Arakawa et al. · Neuropharmacology · 2019 · 16 citations · Full text

Medicine, Neuroscience, Pharmacology +16

Quantification of the purinergic P2X ₇ receptor with [ ¹¹ C]SMW139 improves through correction for brain-penetrating radiometabolites

Joachim Brumberg, Richard Aarnio, Anton Forsberg et al. · Journal of Cerebral Blood Flow & Metabolism · 2022 · 11 citations · Full text

Life Sciences, Neuroscience, Pharmacology +15