Kan Chen

The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models

Stephen T. Durant, Li Zheng, Yingchun Wang et al. · Science Advances · 2018 · 292 citations · Full text

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways

Liwei Wu, Qinghui Zhang, Wenhui Mo et al. · Scientific Reports · 2017 · 260 citations · Full text

Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis

Jiao Feng, Weiqi Dai, Yuqing Mao et al. · Journal of Experimental & Clinical Cancer Research · 2020 · 222 citations · Full text

Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs

Nicola Colclough, Kan Chen, Peter Johnström et al. · Clinical Cancer Research · 2020 · 215 citations · Full text

Endocytosis of soluble immune complexes leads to their clearance by FcγRIIIB but induces neutrophil extracellular traps via FcγRIIA in vivo

Kan Chen, Hiroshi Nishi, Richard J. Travers et al. · Blood · 2012 · 203 citations · Full text