Alexis Ruiz

Quantitative RyR1 reduction and loss of calcium sensitivity of RyR1Q1970fsX16+A4329D cause cores and loss of muscle strength

Moran Elbaz, Alexis Ruiz, Christoph Bachmann et al. · Human Molecular Genetics · 2019 · 31 citations · Full text

Medicine, Genetics, Molecular Genetics +17

Quantitative proteomic analysis of skeletal muscles from wild-type and transgenic mice carrying recessive Ryr1 mutations linked to congenital myopathies

Jan Eckhardt, Alexis Ruiz, Stéphane Koenig et al. · eLife · 2023 · 24 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Screening of GPCR drugs for repurposing in breast cancer

Noor Mazin Abdulkareem, Raksha R. Bhat, Reid T. Powell et al. · Frontiers in Pharmacology · 2022 · 19 citations · Full text

Medicine, Oncology, Pharmacology +15

Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors

Alexis Ruiz, Sofia Benucci, Urs Duthaler et al. · eLife · 2022 · 15 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Quantitative reduction of RyR1 protein caused by a single-allele frameshift mutation in RYR1 ex36 impairs the strength of adult skeletal muscle fibres

Moran Elbaz, Alexis Ruiz, Jan Eckhardt et al. · Human Molecular Genetics · 2019 · 12 citations · Full text

Medicine, Genetics, Molecular Genetics +14