Concepedia

Tina Xiong

TX

Statistics

Publications

8

Citations

232

H-Index

8

Active since

2010

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Johns Hopkins University

Harvard University

Broad Institute

New York University

Tina Xiong is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in life sciences, pharmacology, and potency optimization.

ORCID

Publications per year

2010–2024

8

Publications

8

Targeted DNA methylation in human cells using engineered dCas9-methyltransferases

Tina Xiong, Glenna E. Meister, Rachael E. Workman et al. · Scientific Reports · 2017 · 88 citations · Full text

, , +15

Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors

Mitchell H. Keylor, Anmol Gulati, Solomon D. Kattar et al. · Journal of Medicinal Chemistry · 2021 · 42 citations · Full text

, , +17

Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1 <i>H</i> -Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease

David A. Candito, Vladimir Simov, Anmol Gulati et al. · Journal of Medicinal Chemistry · 2022 · 24 citations · Full text

, , +15

Stability of a guest protein depends on stability of a host protein in insertional fusion

Brennal Pierre, Tina Xiong, Leonie Hayles et al. · Biotechnology and Bioengineering · 2010 · 19 citations

, , +17

Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease

Solomon D. Kattar, Anmol Gulati, Kaila A. Margrey et al. · Journal of Medicinal Chemistry · 2023 · 19 citations · Full text

, , +17

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