Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling

Zhen Gong, Zhongmei Kuang, Hui Li, +9

Cellular Immunology

Pulmonary TuberculosisSignal TransductionCell RegulationCytokines ProductionApoptosis +9

Mycobacterium tuberculosis PE31 (Rv3477) Attenuates Host Cell Apoptosis and Promotes Recombinant M. smegmatis Intracellular Survival via Up-regulating GTPase Guanylate Binding Protein-1

Md Kaisar Ali, Zhen Gong, Nzungize Lambert, +6

Frontiers in Cellular and Infection Microbiology

Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS

Hilary S. Eidam, John P. Russell, Kaushik Raha, +19

ACS Medicinal Chemistry Letters

Characterization and function of Mycobacterium tuberculosis H37Rv Lipase Rv1076 (LipU)

Chunyan Li, Qiming Li, Yuan Zhang, +4

Microbiological Research

Medical MicrobiologyBiochemistryPathogenesisBacteriologyTuberculosis +3

Mycobacterium tuberculosis PE17 (Rv1646) promotes host cell apoptosis via host chromatin remodeling mediated by reduced H3K9me3 occupancy

M. A. Abo-Kadoum, Mohammed Assad, Md Kaisar Ali, +7

Microbial Pathogenesis

ChromatinPulmonary TuberculosisChromatin StructureNatural SciencesHost Cell Apoptosis +8

Cloning and Characterization of the Human USP22 Gene Promoter

Jianjun Xiong, Xiangxin Che, Xueqin Li, +3

PLoS ONE

Usp22 TranscriptionTranscriptional RegulationProtein ExpressionCell RegulationHuman Usp22 Promoter +10

Mycobacterium tuberculosis PPE10 (Rv0442c) alters host cell apoptosis and cytokine profile via linear ubiquitin chain assembly complex HOIP-NF-κB signaling axis

Mohammed Asaad, Md Kaisar Ali, M. A. Abo-Kadoum, +7

International Immunopharmacology

Pulmonary TuberculosisHost Cell ApoptosisApoptosisImmune RegulationImmunology +9

Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR

Tao Yu, Ning Li, Chengde Wu, +18

ACS Medicinal Chemistry Letters

PKA/CREB regulates the constitutive promoter activity of the USP22 gene

Jianjun Xiong, Xiaoou Zhou, Zhen Gong, +5

Oncology Reports

<i>Mycobacterium tuberculosis</i> effector PPE36 attenuates host cytokine storm damage via inhibiting macrophage M1 polarization

Zhen Gong, Shuang Han, Tian Liang, +10

Journal of Cellular Physiology