Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster.

David J. Haile, Tracey A. Rouault, Catherine Tang, +3

Proceedings of the National Academy of Sciences

Iron AvailabilityIron MetabolismMolecular BiologyIron DeficiencyAconitase Activity +18

A regulated RNA binding protein also possesses aconitase activity.

S Kaptain, William E. Downey, Catherine Tang, +6

Proceedings of the National Academy of Sciences

Ire-bp Gene ProductIron MetabolismMolecular BiologyAconitase ActivityRedox Biology +15

Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein.

Tracey A. Rouault, Catherine Tang, S Kaptain, +6

Proceedings of the National Academy of Sciences

Iron MetabolismGeneticsMolecular BiologyRedox BiologyTranscriptional Regulation +16

Isolation and characterization of a new human breast cancer cell line, KPL-4, expressing the Erb B family receptors and interleukin-6

Junichi Kurebayashi, Takemi Otsuki, Catherine Tang, +5

British Journal of Cancer

Anti-HER2 antibody enhances the growth inhibitory effect of anti-oestrogen on breast cancer cells expressing both oestrogen receptors and HER2

Hironori Kunisue, Junichi Kurebayashi, Takemi Otsuki, +7

British Journal of Cancer

Iron regulates the activity of the iron-responsive element binding protein without changing its rate of synthesis or degradation.

Catherine Tang, J Chin, Joe B. Harford, +2

Journal of Biological Chemistry

Iron MetabolismMolecular BiologyIron DeficiencyRedox BiologyOxidative Stress +18

KAI1 protein is down-regulated during the progression of human breast cancer.

Xinyun Yang, Lisa L. Wei, Catherine Tang, +3

PubMed

Breast OncologyKai1 GenePathologyHuman Breast CancerKai1 Mrna Levels +15

AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes

Catherine Tang, Davide Bagnara, Nicholas Chiorazzi, +2

Frontiers in Immunology

GeneticsImmunodeficienciesImmunologyGenomic MechanismMolecular Biology +22

Deep learning model of somatic hypermutation reveals importance of sequence context beyond hotspot targeting

Catherine Tang, Artem Krantsevich, Thomas MacCarthy

iScience

Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in <i>Exo1D173A</i> mice

Shanzhi Wang, Kyeryoung Lee, Stephen Gray, +12

Nucleic Acids Research

Dna DamageGeneticsImmunologyMolecular BiologyCancer Biology +18