Gaopeng Xian

Activation of Piezo1 promotes osteogenic differentiation of aortic valve interstitial cell through YAP-dependent glutaminolysis

Guoheng Zhong, Shuwen Su, Juncong Li et al. · Science Advances · 2023 · 111 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Trimethylamine N-oxide induces osteogenic responses in human aortic valve interstitial cells <i>in vitro</i> and aggravates aortic valve lesions in mice

Jiaying Li, Qingchun Zeng, Zhenyu Xiong et al. · Cardiovascular Research · 2021 · 48 citations

Life Sciences, Cardiology, Cell Biology +14

4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury

Xin Peng, Shuwen Su, Jingxin Zeng et al. · Free Radical Biology and Medicine · 2022 · 29 citations

Life Sciences, Cell Biology, Molecular Biology +17

Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease

Hengli Zhao, Gaopeng Xian, Jingxin Zeng et al. · Antioxidants · 2022 · 15 citations · Full text

Medicine, Cardiology, Pharmacology +17

Noncoding RNA regulates the expression of Krm1 and Dkk2 to synergistically affect aortic valve lesions

Gaopeng Xian, Rong Huang, Minhui Xu et al. · Experimental & Molecular Medicine · 2024 · 12 citations · Full text

Life Sciences, Cardiology, Molecular Biology +17