Neil Smith

Effect of Albumin Binding on Extraction of Sulfobromophthalein by Perfused Elasmobranch Liver: Evidence for Dissociation-Limited Uptake

Richard A. Weisiger, Charles M. Zacks, Neil Smith et al. · Hepatology · 1984 · 55 citations · Full text

Phase I clinical evaluation of CNSA-001 (sepiapterin), a novel pharmacological treatment for phenylketonuria and tetrahydrobiopterin deficiencies, in healthy volunteers

Neil Smith, Nicola Longo, Keith Levert et al. · Molecular Genetics and Metabolism · 2019 · 44 citations

Translational Medicine, Healthy Volunteers, Chronic Kidney Disease +4

PTC923 (sepiapterin) lowers elevated blood phenylalanine in subjects with phenylketonuria: a phase 2 randomized, multi-center, three-period crossover, open-label, active controlled, all-comers study

Drago Bratkovic, Lali Margvelashvili, Michel Tchan et al. · Metabolism · 2021 · 41 citations · Full text

Effects of oral sepiapterin on blood Phe concentration in a broad range of patients with phenylketonuria (APHENITY): results of an international, phase 3, randomised, double-blind, placebo-controlled trial

Ania C. Muntau, Nicola Longo, Fatih Süheyl Ezgü et al. · The Lancet · 2024 · 24 citations

Medicine, Pharmacology, Oral Sepiapterin +5

Relative Oral Bioavailability and Food Effects of Two Sepiapterin Formulations in Healthy Participants

Lan Gao, Diksha Kaushik, Xia Yi et al. · Clinical Pharmacology in Drug Development · 2023 · 12 citations · Full text