Changlin Zhang

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

Zheng Hu, Da Zhu, Wei Wang et al. · Nature Genetics · 2015 · 604 citations

Functional Genomics, Cervical Cancer, Engineering +12

Disruption of HPV16-E7 by CRISPR/Cas System Induces Apoptosis and Growth Inhibition in HPV16 Positive Human Cervical Cancer Cells

Zheng Hu, Lan Yu, Da Zhu et al. · BioMed Research International · 2014 · 206 citations · Full text

Engineering, Cervical Cancer, Cancer-associated Virus +15

Melatonin synergizes the chemotherapeutic effect of 5‐fluorouracil in colon cancer by suppressing <scp>PI</scp>3K/<scp>AKT</scp> and <scp>NF</scp>‐κB/<scp>iNOS</scp> signaling pathways

Yue Gao, Xiangsheng Xiao, Changlin Zhang et al. · Journal of Pineal Research · 2016 · 185 citations

Chemotherapeutic Effect, Cell Death, Cancer Biology +16

NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer

Ge Qin, Xin Wang, Shubiao Ye et al. · Nature Communications · 2020 · 171 citations · Full text

TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy

Zheng Hu, Wencheng Ding, Da Zhu et al. · Journal of Clinical Investigation · 2014 · 124 citations · Full text

Hpv Oncogenes, Molecular Virology, Cervical Cancer +11