J. Robert Coleman

Virus Attenuation by Genome-Scale Changes in Codon Pair Bias

J. Robert Coleman, Dimitris Papamichail, Steven Skiena et al. · Science · 2008 · 728 citations · Full text

Codon Pair Bias, Viral Replication, Synthetic Virology +19

Reduction of the Rate of Poliovirus Protein Synthesis through Large-Scale Codon Deoptimization Causes Attenuation of Viral Virulence by Lowering Specific Infectivity

Steffen Mueller, Dimitris Papamichail, J. Robert Coleman et al. · Journal of Virology · 2006 · 372 citations · Full text

Viral Replication, Synthetic Virology, Genetics +19

Live attenuated influenza virus vaccines by computer-aided rational design

Steffen Mueller, J. Robert Coleman, Dimitris Papamichail et al. · Nature Biotechnology · 2010 · 273 citations · Full text

Vaccination, Design, Influenza Vaccine +5

Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy

Ying Wang, Chen Yang, Yutong Song et al. · Proceedings of the National Academy of Sciences · 2021 · 142 citations · Full text

A codon-pair deoptimized live-attenuated vaccine against respiratory syncytial virus is immunogenic and efficacious in non-human primates

Steffen Mueller, Charles B. Stauft, Raj Kalkeri et al. · Vaccine · 2020 · 57 citations · Full text

Vaccination, Mucosal Vaccination, Vaccine Development +7