David Jay

Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1–XPF

Ahmed H. Elmenoufy, Francesco Gentile, David Jay et al. · Journal of Medicinal Chemistry · 2019 · 29 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Computer‐aided drug design of small molecule inhibitors of the ERCC1‐XPF protein–protein interaction

Francesco Gentile, Ahmed H. Elmenoufy, Gloria Ciniero et al. · Chemical Biology & Drug Design · 2019 · 28 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition

Elizabeth Garcia, I.F. de Luna, Kaya L. Persad et al. · Scientific Reports · 2021 · 28 citations · Full text

Medicine, Oncology, Pharmacology +16

Modulation of ERCC1-XPF Heterodimerization Inhibition via Structural Modification of Small Molecule Inhibitor Side-Chains

Claudia Weilbeer, David Jay, James C. Donnelly et al. · Frontiers in Oncology · 2022 · 16 citations · Full text

Medicine, Oncology, Pharmacology +17

Design, synthesis and in vitro cell-free/cell-based biological evaluations of novel ERCC1-XPF inhibitors targeting DNA repair pathway

Ahmed H. Elmenoufy, Francesco Gentile, David Jay et al. · European Journal of Medicinal Chemistry · 2020 · 13 citations · Full text

Medicine, Medicinal Chemistry, Oncology +16