Chengle Zhuang

Synthesizing AND gate genetic circuits based on CRISPR-Cas9 for identification of bladder cancer cells

Yuchen Liu, Yayue Zeng, Li Liu et al. · Nature Communications · 2014 · 221 citations · Full text

Engineering, Genome Surgery, Medicine +11

Directing cellular information flow via CRISPR signal conductors

Yuchen Liu, Yonghao Zhan, Zhicong Chen et al. · Nature Methods · 2016 · 184 citations

Cell Communication, Medicine, Crispr Signal Conductors +6

N6‐methyladenosine demethylase <scp>FTO</scp> suppresses clear cell renal cell carcinoma through a novel <scp>FTO</scp>‐<scp>PGC</scp>‐1α signalling axis

Changshui Zhuang, Chengle Zhuang, Xiaomin Luo et al. · Journal of Cellular and Molecular Medicine · 2019 · 141 citations · Full text

Engineering, Metabolic Remodeling, Cancer Biology +19

The N6‐methyladenosine modification enhances ferroptosis resistance through inhibiting <i>SLC7A11</i> mRNA deadenylation in hepatoblastoma

Li Liu, Jiangtu He, Guifeng Sun et al. · Clinical and Translational Medicine · 2022 · 138 citations · Full text

Tetracycline-inducible shRNA targeting antisense long non-coding RNA HIF1A-AS2 represses the malignant phenotypes of bladder cancer

Mingwei Chen, Chengle Zhuang, Yuchen Liu et al. · Cancer Letters · 2016 · 90 citations

Tumor Biology, Urology, Non-coding Rna Hif1a-as2 +10