Rebecca S. Cook

RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors

Sherene Loi, Sathana Dushyanthen, Paul A. Beavis et al. · Clinical Cancer Research · 2015 · 546 citations · Full text

Molecular Profiling of the Residual Disease of Triple-Negative Breast Cancers after Neoadjuvant Chemotherapy Identifies Actionable Therapeutic Targets

Justin M. Balko, Jennifer M. Giltnane, Kai Wang et al. · Cancer Discovery · 2013 · 467 citations · Full text

Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

Joan T. Garrett, Maria G. Olivares, Cammie Rinehart et al. · Proceedings of the National Academy of Sciences · 2011 · 455 citations · Full text

Pi3k Pathway, Tumor Biology, Transcriptional Regulation +20

MEK Inhibition Leads to PI3K/AKT Activation by Relieving a Negative Feedback on ERBB Receptors

Alexa B. Turke, Youngchul Song, Carlotta Costa et al. · Cancer Research · 2012 · 355 citations · Full text

Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer

Deanna N. Edwards, Verra M. Ngwa, Ariel Raybuck et al. · Journal of Clinical Investigation · 2020 · 329 citations · Full text

Breast Oncology, Immunology, Tumor Cells +18