High-dimensional immune profiling by mass cytometry revealed immunosuppression and dysfunction of immunity in COVID-19 patients

Wenjing Wang, Bin Su, Lijun Pang, +10

Cellular and Molecular Immunology

Covid-19ImmunodeficienciesMedicineImmunologyImmunophenotyping +8

Downregulated Gene Expression Spectrum and Immune Responses Changed During the Disease Progression in Patients With COVID-19

Yabo Ouyang, Jiming Yin, Wenjing Wang, +10

Clinical Infectious Diseases

The inhibition of IL-2/IL-2R gives rise to CD8+ T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia

Hongbo Shi, Wenjing Wang, Jiming Yin, +8

Cell Death and Disease

CHOP mediates ASPP2-induced autophagic apoptosis in hepatoma cells by releasing Beclin-1 from Bcl-2 and inducing nuclear translocation of Bcl-2

Ke Liu, Ying Shi, Xiaoyu Guo, +8

Cell Death and Disease

Etiology and epidemiology of viral diarrhea in children under the age of five hospitalized in Tianjin, China

Yabo Ouyang, Hui Ma, Min Jin, +10

Archives of Virology

Virus EpidemiologyViral DiarrheaPediatric EpidemiologyPediatricsGastroenterology +8

CD133+ cancer stem cells promoted by VEGF accelerate the recurrence of hepatocellular carcinoma

Kai Liu, Meijun Hao, Yabo Ouyang, +2

Scientific Reports

Heterogeneity induced GZMA-F2R communication inefficient impairs antitumor immunotherapy of PD-1 mAb through JAK2/STAT1 signal suppression in hepatocellular carcinoma

Yuxue Gao, Qingguo Xu, Xinqiang Li, +14

Cell Death and Disease

Phosphorylated AKT inhibits the apoptosis induced by DRAM-mediated mitophagy in hepatocellular carcinoma by preventing the translocation of DRAM to mitochondria

Ke Liu, Ying Shi, Xiaoyu Guo, +6

Cell Death and Disease

MitophagyDram-mediated MitophagyDamage-regulated Autophagy ModulatorApoptosisPathology +16

Trends in hepatitis B virus resistance to nucleoside/nucleotide analogues in North China from 2009–2016: A retrospective study

Xianghua Guo, Jushan Wu, Feili Wei, +6

International Journal of Antimicrobial Agents

Design, Synthesis, and Biological Evaluation of 1-[(2-Benzyloxyl/alkoxyl)methyl]-5-halo-6-aryluracils as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with an Improved Drug Resistance Profile

Xiaowei Wang, Jianfang Zhang, Yang Huang, +13

Journal of Medicinal Chemistry

PharmacotherapyPotent Anti-hiv-1 ActivityNnrti-resistant Hiv-1 StrainsAntiviral DrugDrug Resistance +15