Jian Jin

Selective Synthesis of Isoquinolines by Rhodium(III)-Catalyzed C–H/N–H Functionalization with α-Substituted Ketones

Jie Li, Zhao Zhang, Mengyao Tang et al. · Organic Letters · 2016 · 51 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14

Discovery of novel selective PI3Kγ inhibitors through combining machine learning-based virtual screening with multiple protein structures and bio-evaluation

Jingyu Zhu, Kan Li, Lei Xu et al. · Journal of Advanced Research · 2021 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Integrating Machine Learning-Based Virtual Screening With Multiple Protein Structures and Bio-Assay Evaluation for Discovery of Novel GSK3β Inhibitors

Jingyu Zhu, Yuanqing Wu, Man Wang et al. · Frontiers in Pharmacology · 2020 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Inhibition of B7-H3 reverses oxaliplatin resistance in human colorectal cancer cells

Zhen Chen, Kuan Ning, Jian Jin et al. · Biochemical and Biophysical Research Communications · 2017 · 41 citations

Medicine, Oncology, Pharmacology +13

Theoretical Studies on the Selectivity Mechanisms of Glycogen Synthase Kinase 3β (GSK3β) with Pyrazine ATP-competitive Inhibitors by 3DQSAR, Molecular Docking, Molecular Dynamics Simulation and Free Energy Calculations

Jingyu Zhu, Yuanqing Wu, Lei Xu et al. · Current Computer - Aided Drug Design · 2019 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17