Linyu Chen

Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat

Lan Zhang, Huiying Zhao, Xiangjian Zhang et al. · Brain Research Bulletin · 2013 · 104 citations

Bcl-2 Pathway, Cerebral Ischemia, Cerebral Vascular Regulation +13

Nobiletin promotes antioxidant and anti-inflammatory responses and elicits protection against ischemic stroke in vivo

Lan Zhang, Xiangjian Zhang, Cong Zhang et al. · Brain Research · 2016 · 95 citations

Inflammation, Thrombosis, Cerebral Vascular Regulation +14

Protection by silibinin against experimental ischemic stroke: Up-regulated pAkt, pmTOR, HIF-1α and Bcl-2, down-regulated Bax, NF-κB expression

Chaohui Wang, Zhihong Wang, Xiangjian Zhang et al. · Neuroscience Letters · 2012 · 92 citations

Immunology, Cerebrovascular Disease, Pharmacotherapy +16

Protective Effect of Luteolin in Experimental Ischemic Stroke: Upregulated SOD1, CAT, Bcl-2 and Claudin-5, Down-Regulated MDA and Bax Expression

Huimin Qiao, Lipeng Dong, Xiangjian Zhang et al. · Neurochemical Research · 2012 · 84 citations

Bax Expression, Cerebrovascular Disease, Cerebral Vascular Regulation +16

Protective Effect of Shikonin in Experimental Ischemic Stroke: Attenuated TLR4, p-p38MAPK, NF-κB, TNF-α and MMP-9 Expression, Up-Regulated Claudin-5 Expression, Ameliorated BBB Permeability

Lina Wang, Zhenzhong Li, Xiangjian Zhang et al. · Neurochemical Research · 2013 · 80 citations

Vascular Disease, Immunology, Cerebral Vascular Regulation +16