Carlos Roca

Tau-Centric Multitarget Approach for Alzheimer’s Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors

Annachiara Gandini, Manuela Bartolini, Daniele Tedesco et al. · Journal of Medicinal Chemistry · 2018 · 102 citations · Full text

Hybridizing Feature Selection and Feature Learning Approaches in QSAR Modeling for Drug Discovery

Ignacio Ponzoni, Víctor Sebastián-Pérez, Carlos Requeña et al. · Scientific Reports · 2017 · 69 citations · Full text

Engineering, Machine Learning, Hit Identification +22

QSAR Classification Models for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer’s Disease

Ignacio Ponzoni, Víctor Sebastián-Pérez, María Jimena Martínez et al. · Scientific Reports · 2019 · 68 citations · Full text

Subtly Modulating Glycogen Synthase Kinase 3 β: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases

Valle Palomo, Daniel I. Pérez, Carlos Roca et al. · Journal of Medicinal Chemistry · 2017 · 67 citations · Full text

Molecular Pharmacology, Allosteric Modulators, Glycogen Synthase +14

AI in drug development: a multidisciplinary perspective

Víctor Gallego, Roi Naveiro, Carlos Roca et al. · Molecular Diversity · 2021 · 67 citations · Full text